{"id":80998,"date":"2018-08-25T17:00:11","date_gmt":"2018-08-25T14:00:11","guid":{"rendered":"http:\/\/e-shocknews.com\/?p=80998"},"modified":"2018-08-25T18:36:38","modified_gmt":"2018-08-25T15:36:38","slug":"%ce%b3%ce%bf%ce%bd%ce%af%ce%b4%ce%b9%ce%bf-%ce%b6%cf%8c%ce%bc%cf%80%ce%b9-%cf%80%ce%bf%cf%85-%cf%83%ce%ba%ce%bf%cf%84%cf%8e%ce%bd%ce%b5%ce%b9-%cf%84%ce%bf%ce%bd-%ce%ba%ce%b1%cf%81","status":"publish","type":"post","link":"https:\/\/e-shocknews.com\/?p=80998","title":{"rendered":"\u0393\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u00ab\u03b6\u03cc\u03bc\u03c0\u03b9\u00bb \u03c0\u03bf\u03c5 \u00a0\u03c3\u03ba\u03bf\u03c4\u03ce\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b5\u03bb\u03ad\u03c6\u03b1\u03bd\u03c4\u03b5\u03c2"},"content":{"rendered":"<p>\u03a0\u03b5\u03c1\u03af\u03c0\u03bf\u03c5 30 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\u03c0\u03bf\u03bb\u03cd \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03ac. \u0391\u03bb\u03bb\u03ac \u03b1\u03c5\u03c4\u03cc \u03b4\u03b5\u03bd \u03c3\u03c5\u03bc\u03b2\u03b1\u03af\u03bd\u03b5\u03b9 \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03bf\u03bd\u03b5\u03c2 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c9\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03bf\u03bd\u03c4\u03ac \u03c3\u03c4\u03bf \u03bd\u03b1 \u03b1\u03c0\u03bf\u03ba\u03c9\u03b4\u03b9\u03ba\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03bf\u03c5\u03bd \u03c4\u03bf \u03bc\u03c5\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03b1\u03c5\u03c4\u03cc.<\/p>\n<p>\u039c\u03b9\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c3\u03c4\u03bf \u03c0\u03b5\u03c1\u03b9\u03bf\u03b4\u03b9\u03ba\u03cc Cell Reports \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03b5\u03b9 \u03bd\u03ad\u03b5\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 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\u03c4\u03b7\u03c2 \u0393\u03b9\u03bf\u03cd\u03c4\u03b1, \u03bf \u03bf\u03c0\u03bf\u03af\u03bf\u03c2 \u03b4\u03b5\u03bd \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03b5\u03af\u03c7\u03b5 \u03c3\u03c4\u03b7\u03bd \u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1. \u00ab\u0391\u03c5\u03c4\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03c3\u03c0\u03bf\u03c5\u03b4\u03b1\u03af\u03b1 \u03b1\u03c1\u03c7\u03ae\u00bb, \u03bb\u03ad\u03b5\u03b9.<\/p>\n<p>\u03a4\u03bf 2015, \u03bf Schiffman \u03ba\u03b1\u03b9 \u03b7 \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c4\u03bf\u03c5 \u03b4\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b1\u03bd \u03ad\u03bd\u03b1 \u03ad\u03b3\u03b3\u03c1\u03b1\u03c6\u03bf \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03ac\u03c6\u03b5\u03b9 \u03bc\u03b9\u03b1 \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03b7 \u03b1\u03bd\u03b1\u03ba\u03ac\u03bb\u03c5\u03c8\u03b7 \u03c0\u03af\u03c3\u03c9 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03bd\u03c4\u03b9\u03c3\u03c4\u03bf\u03b9\u03c7\u03af\u03b1 \u03c4\u03bf\u03c5 \u03bc\u03b5\u03b3\u03ad\u03b8\u03bf\u03c5\u03c2 \u03c4\u03c9\u03bd \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03ce\u03bd \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03ce\u03bd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 &#8211; \u03ad\u03bd\u03b1 \u03b6\u03ae\u03c4\u03b7\u03bc\u03b1 \u03c0\u03bf\u03c5 \u03c4\u03ce\u03c1\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03bd\u03c9\u03c3\u03c4\u03cc \u03c9\u03c2 \u03a0\u03b1\u03c1\u03ac\u03b4\u03bf\u03be\u03bf \u03c4\u03bf\u03c5 Peto.<\/p>\n<p>\u0394\u03b9\u03b1\u03c0\u03af\u03c3\u03c4\u03c9\u03c3\u03b1\u03bd \u03cc\u03c4\u03b9 <b>\u03bf\u03b9 \u03b5\u03bb\u03ad\u03c6\u03b1\u03bd\u03c4\u03b5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03b1\u03bd\u03c4\u03af\u03b3\u03c1\u03b1\u03c6\u03b1 \u03b5\u03bd\u03cc\u03c2 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u03cc\u03b3\u03ba\u03c9\u03bd \u03c0\u03bf\u03c5 \u03bf\u03bd\u03bf\u03bc\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 P53.<\/b> <b>\u039f\u03b9 \u03ac\u03bd\u03b8\u03c1\u03c9\u03c0\u03bf\u03b9 \u03ad\u03c7\u03bf\u03c5\u03bd \u03ad\u03bd\u03b1 \u03b1\u03bd\u03c4\u03af\u03b3\u03c1\u03b1\u03c6\u03bf, \u03b1\u03bb\u03bb\u03ac \u03bf\u03b9 \u03b5\u03bb\u03ad\u03c6\u03b1\u03bd\u03c4\u03b5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd 20.<\/b><\/p>\n<p>\u039a\u03b1\u03b8\u03ce\u03c2 \u03c4\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03b6\u03ce\u03bf\u03c5 \u03c7\u03c9\u03c1\u03af\u03b6\u03bf\u03c5\u03bd, \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u03b4\u03c1\u03b1 \u03c9\u03c2 \u03ad\u03bd\u03b1\u03c2 \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c0\u03b5\u03cd\u03b8\u03c5\u03bd\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03c4\u03b1\u03be\u03b9\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03b8\u03bf\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03bf \u03bc\u03ad\u03bb\u03bb\u03bf\u03bd \u03c4\u03c9\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd.<\/p>\n<p>\u00ab\u03a4\u03bf P53 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03af\u03c3\u03b5\u03b9 \u03c4\u03b7 \u03b2\u03bb\u03ac\u03b2\u03b7 \u03c3\u03c4\u03bf DNA \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03ac \u03bd\u03b1 \u03ba\u03ac\u03bd\u03b5\u03b9 \u03c1\u03c5\u03b8\u03bc\u03af\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c4\u03b9\u03c2 \u03b5\u03c0\u03b9\u03bb\u03bf\u03b3\u03ad\u03c2\u00bb, \u03b5\u03be\u03b7\u03b3\u03b5\u03af \u03b7 Amy Boddy, \u03b2\u03b9\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 \u03c3\u03c4\u03bf \u03a0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03b9\u03bf \u03c4\u03b7\u03c2 \u039a\u03b1\u03bb\u03b9\u03c6\u03cc\u03c1\u03bd\u03b9\u03b1\u03c2.<\/p>\n<p>\u039a\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03bc\u03b5 \u03b4\u03b5\u03c5\u03c4\u03b5\u03c1\u03b5\u03cd\u03bf\u03bd\u03c4\u03b1 \u03c0\u03c1\u03bf\u03b2\u03bb\u03ae\u03bc\u03b1\u03c4\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b5\u03c0\u03b9\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03bf\u03cd\u03bd, \u03b1\u03bb\u03bb\u03ac \u03b5\u03ac\u03bd \u03ad\u03c7\u03bf\u03c5\u03bd \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7 \u03b6\u03b7\u03bc\u03b9\u03ac, \u03c4\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03b3\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c2, \u03bf\u03c0\u03cc\u03c4\u03b5 \u03c4\u03bf P53 \u03b4\u03b9\u03b1\u03c4\u03ac\u03b6\u03b5\u03b9 \u03bd\u03b1 \u03b8\u03b1\u03bd\u03b1\u03c4\u03c9\u03b8\u03bf\u03cd\u03bd.<\/p>\n<p>\u0395\u03bd\u03ce \u03c4\u03b1 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b6\u03ce\u03b1 \u03b5\u03c0\u03b9\u03bb\u03ad\u03b3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03c3\u03ba\u03b5\u03c5\u03ae, \u03c4\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03c4\u03c9\u03bd \u03b5\u03bb\u03b5\u03c6\u03ac\u03bd\u03c4\u03c9\u03bd \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03bf\u03cd\u03bd \u03c0\u03b9\u03bf \u03c3\u03c5\u03c7\u03bd\u03ac \u03c4\u03b7\u03bd \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03b4\u03b9\u03b1\u03b4\u03c1\u03bf\u03bc\u03ae \u03c4\u03b7\u03c2 \u03b5\u03ba\u03c4\u03ad\u03bb\u03b5\u03c3\u03b7\u03c2, \u03b5\u03be\u03b7\u03b3\u03b5\u03af \u03bf \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03ad\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 Vincent Lynch, \u03ad\u03bd\u03b1\u03c2 \u03b5\u03be\u03b5\u03bb\u03b9\u03ba\u03c4\u03b9\u03ba\u03cc\u03c2 \u03b2\u03b9\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2 \u03c3\u03c4\u03bf \u03a0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03b9\u03bf \u03c4\u03bf\u03c5 \u03a3\u03b9\u03ba\u03ac\u03b3\u03bf\u03c5.<\/p>\n<p>\u00ab\u039f\u03b9 \u03b5\u03bb\u03ad\u03c6\u03b1\u03bd\u03c4\u03b5\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03be\u03b9\u03bf\u03b8\u03b1\u03cd\u03bc\u03b1\u03c3\u03c4\u03bf\u03b9\u00bb, \u03bb\u03ad\u03b5\u03b9 \u00ab\u03a4\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c0\u03bb\u03ce\u03c2 \u03c0\u03b5\u03b8\u03b1\u03af\u03bd\u03bf\u03c5\u03bd \u03b1\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03b5\u03af \u03b2\u03bb\u03ac\u03b2\u03b7 \u03c3\u03c4\u03bf DNA\u00bb, \u03bb\u03ad\u03b5\u03b9 \u03bf Lynch, \u03bf \u03bf\u03c0\u03bf\u03af\u03bf\u03c2 \u03b7\u03b3\u03ae\u03b8\u03b7\u03ba\u03b5 \u03c4\u03b7\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b1\u03c2 \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b5\u03be\u03ac\u03c1\u03c4\u03b7\u03c4\u03b1 \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03af\u03c9\u03c3\u03b5 \u03c4\u03b1 \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03b1 P53 \u03c4\u03c9\u03bd \u03b5\u03bb\u03b5\u03c6\u03ac\u03bd\u03c4\u03c9\u03bd.<\/p>\n<p>\u039f Lynch \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03c3\u03c5\u03bd\u03b5\u03c1\u03b3\u03ac\u03c4\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03ac\u03c1\u03c7\u03b9\u03c3\u03b1\u03bd \u03bd\u03b1 \u03c8\u03ac\u03c7\u03bd\u03bf\u03c5\u03bd \u03b3\u03b9\u03b1 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ad\u03c2 \u03c3\u03b5 \u03b5\u03bb\u03ad\u03c6\u03b1\u03bd\u03c4\u03b5\u03c2 \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03bc\u03b9\u03ba\u03c1\u03ac \u03b8\u03b7\u03bb\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac, \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03b3\u03b9\u03b1 \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03b1 \u03bc\u03b5 \u03b5\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd \u03b1\u03bd\u03c4\u03af\u03b3\u03c1\u03b1\u03c6\u03b1.<\/p>\n<p>\u0388\u03bd\u03b1 \u03c0\u03bf\u03c5 \u03be\u03b5\u03c7\u03ce\u03c1\u03b9\u03b6\u03b5 \u03ae\u03c4\u03b1\u03bd \u03bf \u0391\u03bd\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03cc\u03c2 \u03a0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u039b\u03b5\u03c5\u03c7\u03b1\u03b9\u03bc\u03af\u03b1\u03c2 \u03ae \u03bf LIF, \u03bf \u03bf\u03c0\u03bf\u03af\u03bf\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b3\u03bd\u03c9\u03c3\u03c4\u03cc\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf \u03c1\u03cc\u03bb\u03bf \u03c4\u03bf\u03c5 \u03c3\u03c4\u03b7\u03bd \u03b5\u03bd\u03af\u03c3\u03c7\u03c5\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b3\u03bf\u03bd\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2.<\/p>\n<p>\u0397 \u03b3\u03bf\u03bd\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b1\u03ba\u03c1\u03b9\u03ac \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5, \u03b1\u03bb\u03bb\u03ac \u03bf Lynch \u03c0\u03b9\u03c3\u03c4\u03b5\u03cd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf LIF6 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03bd\u03b1 \u03b5\u03be\u03c5\u03c0\u03b7\u03c1\u03b5\u03c4\u03ae\u03c3\u03b5\u03b9 \u03bc\u03b9\u03b1 \u03ac\u03bb\u03bb\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1: \u03bd\u03b1 \u03c3\u03ba\u03bf\u03c4\u03ce\u03c3\u03b5\u03b9 \u03c4\u03b1 \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03c1\u03b1\u03bc\u03bc\u03ad\u03bd\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1.<\/p>\n<div>\u03a4\u03b1 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b8\u03b7\u03bb\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03ad\u03c7\u03bf\u03c5\u03bd \u03bc\u03cc\u03bd\u03bf \u03ad\u03bd\u03b1 \u03b1\u03bd\u03c4\u03af\u03b3\u03c1\u03b1\u03c6\u03bf \u03c4\u03bf\u03c5 LIF. \u0391\u03bb\u03bb\u03ac \u03bf\u03b9 \u03b5\u03bb\u03ad\u03c6\u03b1\u03bd\u03c4\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03c3\u03c4\u03b5\u03bd\u03bf\u03af \u03c3\u03c5\u03b3\u03b3\u03b5\u03bd\u03b5\u03af\u03c2 \u03c4\u03bf\u03c5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03c0\u03bf\u03bb\u03bb\u03ac. \u039f\u03b9 \u03b5\u03bb\u03ad\u03c6\u03b1\u03bd\u03c4\u03b5\u03c2 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03ad\u03c7\u03bf\u03c5\u03bd 7 \u03ad\u03c9\u03c2 11.<\/div>\n<div><\/div>\n<div><\/div>\n<p>\u0388\u03bd\u03b1 \u03bc\u03cc\u03bd\u03bf \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03ac \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03b5\u03be\u03c5\u03c0\u03b7\u03c1\u03b5\u03c4\u03b5\u03af \u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03b5\u03ba\u03c4\u03ad\u03bb\u03b5\u03c3\u03b7\u03c2: \u03c4\u03bf LIF6. \u039a\u03b1\u03b9 \u03bc\u03ad\u03c7\u03c1\u03b9 \u03c3\u03c4\u03b9\u03b3\u03bc\u03ae\u03c2 \u03c4\u03bf \u03b2\u03c1\u03ae\u03ba\u03b1\u03bd \u03bc\u03cc\u03bd\u03bf \u03c3\u03b5 \u03b5\u03bb\u03ad\u03c6\u03b1\u03bd\u03c4\u03b5\u03c2. \u03a4\u03bf LIF6 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03c3\u03c4\u03b7\u03ba\u03b5 \u03c3\u03b5 \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03b1 \u03b5\u03bb\u03b5\u03c6\u03ac\u03bd\u03c4\u03c9\u03bd \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc 59 \u03b5\u03ba\u03b1\u03c4\u03bf\u03bc\u03bc\u03cd\u03c1\u03b9\u03b1 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1, \u03c3\u03cd\u03bc\u03c6\u03c9\u03bd\u03b1 \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03c3\u03c5\u03bd\u03c4\u03ac\u03ba\u03c4\u03b5\u03c2 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2. \u039a\u03b1\u03b9 \u03b1\u03c1\u03c7\u03b9\u03ba\u03ac, \u03ae\u03c4\u03b1\u03bd \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc \u03ad\u03bd\u03b1 \u03ac\u03c7\u03c1\u03b7\u03c3\u03c4\u03bf \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf.<\/p>\n<p>\u038c\u03bc\u03c9\u03c2, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03bf\u03b9 \u03c0\u03c1\u03cc\u03b3\u03bf\u03bd\u03bf\u03b9 \u03c4\u03c9\u03bd \u03b5\u03bb\u03b5\u03c6\u03ac\u03bd\u03c4\u03c9\u03bd \u03b5\u03be\u03b5\u03bb\u03af\u03c7\u03b8\u03b7\u03ba\u03b1\u03bd, \u03c4\u03bf \u03af\u03b4\u03b9\u03bf \u03ad\u03ba\u03b1\u03bd\u03b5 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf. \u03a4\u03b5\u03bb\u03b9\u03ba\u03ac \u03b5\u03be\u03b5\u03bb\u03af\u03c7\u03b8\u03b7\u03ba\u03b5 \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03cc \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf &#8220;\u03b6\u03cc\u03bc\u03c0\u03b9&#8221; &#8211; \u03bc\u03b9\u03b1 \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03b5\u03bb\u03ad\u03c6\u03b1\u03bd\u03c4\u03b5\u03c2 \u03bd\u03b1 \u03c6\u03c4\u03ac\u03c3\u03bf\u03c5\u03bd \u03c3\u03b5 \u03c4\u03ad\u03c4\u03bf\u03b9\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5\u03b3\u03ad\u03b8\u03b7 \u03c7\u03c9\u03c1\u03af\u03c2 \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf. \u0391\u03bd \u03c4\u03bf P53 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c0\u03b5\u03cd\u03b8\u03c5\u03bd\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae \u03c4\u03b1\u03be\u03b9\u03bd\u03cc\u03bc\u03b7\u03c3\u03b7, \u03c4\u03bf LIF6 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c0\u03b5\u03cd\u03b8\u03c5\u03bd\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b5\u03ba\u03c4\u03ad\u03bb\u03b5\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b5\u03bd\u03c4\u03bf\u03bb\u03ce\u03bd \u03c4\u03bf\u03c5: \u03c4\u03b7\u03bd \u03b5\u03be\u03ac\u03bb\u03b5\u03b9\u03c8\u03b7 \u03c4\u03c9\u03bd \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03c1\u03b1\u03bc\u03bc\u03ad\u03bd\u03c9\u03bd \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd.<\/p>\n<p>\u039f Lynch \u03ba\u03b1\u03b9 \u03b7 \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c4\u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03c4\u03b7 \u03b4\u03c1\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5 LIF6 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ce\u03bd\u03c4\u03b1\u03c2 \u03b2\u03bb\u03ac\u03b2\u03b7 \u03c4\u03bf\u03c5 DNA \u03c3\u03c4\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c6\u03c1\u03b9\u03ba\u03b1\u03bd\u03b9\u03ba\u03ce\u03bd \u03b5\u03bb\u03b5\u03c6\u03ac\u03bd\u03c4\u03c9\u03bd \u03c3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf. \u0391\u03c5\u03c4\u03ae \u03b7 \u03b2\u03bb\u03ac\u03b2\u03b7 \u03c6\u03ac\u03bd\u03b7\u03ba\u03b5 \u03bd\u03b1 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b5\u03af \u03c4o \u03a153 \u03ce\u03c3\u03c4\u03b5 \u03b1\u03c5\u03c4\u03cc \u03bd\u03b1 \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9 \u03bc\u03b5\u03c4\u03ac \u03c4\u03bf \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf LIF6, \u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03ad\u03c0\u03b5\u03b9\u03c4\u03b1 \u03c3\u03ba\u03cc\u03c4\u03c9\u03c3\u03b5 \u03c4\u03b1 \u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03c1\u03b1\u03bc\u03bc\u03ad\u03bd\u03b1 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1. \u0391\u03bd \u03cc\u03bc\u03c9\u03c2 \u03b5\u03bc\u03c0\u03cc\u03b4\u03b9\u03b6\u03b1\u03bd \u03c4\u03bf LIF6 \u03bd\u03b1 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03ae\u03c3\u03b5\u03b9, \u03b7 \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b9\u03c2 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ad\u03c2 \u03b2\u03bb\u03ac\u03b2\u03b5\u03c2 \u03c6\u03b1\u03b9\u03bd\u03cc\u03c4\u03b1\u03bd \u03bd\u03b1 \u03b5\u03be\u03b1\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9, \u03bb\u03ad\u03b5\u03b9 \u03bf Lynch.<\/p>\n<p>\u0394\u03af\u03ba\u03c4\u03c5\u03b1 \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03a4\u03bf \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u03b6\u03cc\u03bc\u03c0\u03b9 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03bc\u03cc\u03bd\u03bf \u03c0\u03bf\u03c5 \u03ba\u03c1\u03b1\u03c4\u03ac \u03c4\u03bf\u03bd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf \u03c5\u03c0\u03cc \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf, \u03c0\u03c1\u03bf\u03b5\u03b9\u03b4\u03bf\u03c0\u03bf\u03b9\u03b5\u03af \u03bf Lynch. \u00ab\u03a4\u03bf LIF6 \u03c0\u03b1\u03af\u03b6\u03b5\u03b9 \u03ad\u03bd\u03b1 \u03bc\u03b9\u03ba\u03c1\u03cc \u03c1\u03cc\u03bb\u03bf \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03b5\u03c5\u03c1\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1\u00bb, \u03bb\u03ad\u03b5\u03b9. \u0397 \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c4\u03bf\u03c5 \u03b4\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b5 \u03bc\u03b9\u03b1 \u03c4\u03ad\u03c4\u03bf\u03b9\u03b1 \u03b1\u03bd\u03b1\u03ba\u03ac\u03bb\u03c5\u03c8\u03b7 \u03bd\u03c9\u03c1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c6\u03ad\u03c4\u03bf\u03c2, \u03b5\u03c0\u03b9\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03b8\u03b7\u03ba\u03b5 \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03ac\u03bb\u03bb\u03bf \u03c3\u03cd\u03bd\u03bf\u03bb\u03bf \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bd \u03c0\u03bf\u03c5 \u03b2\u03bf\u03b7\u03b8\u03bf\u03cd\u03bd 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